Chinsunate Injection (1Ml) (1 Ml Amp) Artesunate 60 Mg + Sodium Bicarbonate 5% W/V + Sodium Chloride 0.9% W/V By Alkem

Composition

Artesunate 60 mg \+ Sodium Bicarbonate 5% w/v + Sodium Chloride 0.9% w/v

This is an injectable antimalarial preparation. Artesunate is supplied with sodium bicarbonate for reconstitution and sodium chloride as a diluent, depending on the specific kit/product.

- Artesunate — rapidly kills malaria parasites, particularly _Plasmodium falciparum_.
- Sodium bicarbonate — used during preparation/reconstitution of artesunate injection.
- Sodium chloride 0.9% — used as a compatible diluent when specified by the product instructions.

Uses

Injectable artesunate is primarily used for severe malaria, including severe _P. falciparum_ malaria.

Severe malaria can involve:

- Altered consciousness or coma
- Severe anaemia
- Respiratory difficulty
- Shock
- Kidney impairment
- Very high parasite levels
- Low blood sugar

It is an emergency condition requiring hospital treatment.

How to Use

Artesunate injection should be prepared and administered by trained healthcare professionals.

The dose is based mainly on body weight and severity of malaria, rather than simply on the 60-mg vial strength. The treatment schedule and route (IV or IM) should follow the specific product instructions and current malaria treatment protocol.

After initial injectable treatment and once the patient can take oral medicines, treatment is generally followed by a complete oral antimalarial regimen to ensure the infection is fully cleared.

Do not self-inject or attempt to prepare the injection at home.

Precautions & Warnings

Tell the healthcare team if the patient has:

- Previous allergy to artesunate or related medicines
- Significant liver or kidney problems
- Pregnancy
- Other serious medical conditions

Delayed haemolytic anaemia can occur after artesunate treatment, sometimes days or weeks after therapy. Follow-up blood counts may therefore be required, particularly after treatment for severe malaria.

Possible Side Effects

Possible effects include:

- Nausea or vomiting
- Dizziness
- Headache
- Injection-site reactions
- Changes in blood counts

Important but less common complications include delayed haemolytic anaemia and allergic reactions.

Seek urgent medical attention for difficulty breathing, severe rash, jaundice, unusual weakness, dark urine, fainting, or other signs of significant anaemia or an allergic reaction.

Pregnancy & Breastfeeding

Artesunate is an important treatment for severe malaria during pregnancy when medically indicated. Untreated severe malaria can be dangerous for both mother and baby. Treatment should be administered under medical supervision.

Storage

Store the unopened vials according to the manufacturer's instructions. Reconstituted artesunate has specific stability requirements and should be prepared and used according to the product instructions.

Important Safety Information

Severe malaria requires urgent hospital treatment. Artesunate injection rapidly reduces the parasite burden but is normally part of a complete antimalarial treatment plan rather than a standalone course.

If you are asking about the 60-mg artesunate injection dose for an adult or child, tell me the patient's weight and whether the malaria is classified as severe, and I can explain the standard dosing approach.