Dapaking Gm1 Forte Xr Tablets (Glimepiride 1 mg + Metformin Hydrochloride 1000 mg + Dapagliflozin 10 mg)

Composition:

Glimepiride 1 mg,Metformin Hydrochloride (XR) 1000 mg,Dapagliflozin 10 mg
Therapeutic Class: Oral Antidiabetic (Triple Combination Therapy)

Description

Dapaking GM1 Forte XR Tablet combines three complementary antidiabetic agents to provide comprehensive glycemic control in Type 2 Diabetes Mellitus (T2DM).

Glimepiride – A sulfonylurea that stimulates pancreatic insulin secretion.

Metformin XR – A biguanide that reduces hepatic glucose output and improves insulin sensitivity.

Dapagliflozin – A SGLT2 inhibitor that enhances urinary glucose excretion, contributing to lower blood glucose, modest weight reduction, and blood pressure benefits.

This once-daily XR formulation simplifies dosing and promotes sustained glycemic control throughout the day.

Warnings and Precautions

Hypoglycemia: Risk due to Glimepiride; counsel patients on early symptoms.

Lactic Acidosis: Possible with Metformin in renal, hepatic, or hypoxic states.

Genital/Urinary Infections: Common with Dapagliflozin; advise hygiene maintenance.

Volume Depletion: Monitor hydration and renal function.

Weight Loss: Mild to moderate reduction may occur.

Adverse Effects

Common:Hypoglycemia, nausea, diarrhea, polyuria, headache, dizziness, genital infections.

Occasional: Fatigue, dehydration, mild hypotension.

Rare but Serious: Lactic acidosis, severe hypoglycemia, hypersensitivity reactions.

Storage

Store below 30 °C, protected from moisture and light.

Keep out of reach of children.