Dapaking Gm2 Forte Xr Tablets (Glimepiride 2 mg + Metformin Hydrochloride 1000 mg + Dapagliflozin 10 mg)

Composition:

Glimepiride 2 mg,Metformin Hydrochloride (XR) 1000 mg,Dapagliflozin 10 mg
Therapeutic Class: Oral Antidiabetic / Triple Combination Therapy

Description

Dapaking GM2 Forte XR Tablet is a triple oral antidiabetic combination used for effective management of Type 2 Diabetes Mellitus (T2DM). It targets three key mechanisms of blood glucose control:

Glimepiride: A sulfonylurea that enhances insulin secretion from pancreatic β-cells.

Metformin XR: A biguanide that reduces hepatic glucose output and improves peripheral insulin sensitivity.

Dapagliflozin: A SGLT2 inhibitor that promotes urinary glucose excretion, contributing to glycemic control and potential weight loss.

Together, these agents provide comprehensive glycemic control, reduce HbA1c effectively, and lower the risk of diabetes-related complications.

Warnings and Precautions

Hypoglycemia Risk: Due to Glimepiride; monitor blood glucose closely.

Lactic Acidosis: Possible with Metformin; avoid in renal dysfunction or hypoxic conditions.

Genital/Urinary Infections: Common with Dapagliflozin; maintain good hygiene.

Volume Depletion: Monitor hydration and renal function in elderly or diuretic-treated patients.

Weight Loss: May occur due to SGLT2 inhibition.

Adverse Effects

Common:

Hypoglycemia, nausea, diarrhea, polyuria, headache, dizziness, genital infections.

Serious (rare):

Lactic acidosis, severe hypoglycemia, dehydration, hypersensitivity reactions.

Storage

Store below 30°C, protected from light and moisture.

Keep out of reach of children.